When the Calm Rebounds: Understanding Xanax Withdrawal Symptoms
Why Withdrawal Happens: Brain Adaptation, Tolerance, and Timing Alprazolam, commonly known as Xanax, works by enhancing the effects of gamma-aminobutyric acid (GABA), the brain’s major inhibitory neurotransmitter. Over time, the brain adapts to this constant boost in inhibition by reducing GABA receptor sensitivity and increasing excitatory activity. When the medication is reduced or stopped abruptly,